These facilities are located in the Integrated Sciences Complex (ISC), opened in Spring 2015 (when most of the equipment was purchased) on the UMass campus at 100 Morrissey Blvd. in Boston. It is a 30-minute trip door-to-door on the Red Line from Kendall to UMass. For your convenience, a new 1,400 parking garage adjacent to the ISC is open.
The 7,515 square foot Animal Vivarium is located on the 5th floor of the ISC, and comprises:
• 16 housing rooms, independently controlled housing cubicles, pass-through cage washer and autoclave, operation room, one necropsy room, and three procedure rooms.
• Staffed 7-days a week, offering routine husbandry and breeding care for the animals.
• The Barrier Suite allows for the housing and use of immunocompromised mice, including the following equipment:
Key Equipment: Getinge GE6613 ERB 2 Door Steam Sterilizer for sterilizing immunocompromised mouse cages, water bottles, bedding, and other husbandry components. Perkin Elmer IVIS Lumina XRMS Series III instrument for visualizing tumor growth, response to chemotherapeutic agents, and assessment of tumor biomarkers in vivo and in real time without sacrificing the host animal.
Major Equipment: Objet30 3D Printer (for biocompatible materials), Roland MDX-540SA milling instrument, Markforged Mark 2 (for carbon fiber reinforced parts), Ultimaker 2 (fused deposition modeling 3D printer), GCC LaserPro Spirit LS, Roland MDX-40A Milling Machine, and Formlabs Form 2 3D printer.
Major Equipment: Agilent 400 MHz NMR, PerkinElmer AxION 2 TOF LC-MS, Isotope Ratio Mass Spectrometer (IR-MS), Gas Chromatography Mass Spectrometer (GC-MS), Inductively Coupled Plasma Mass Spectrometer (ICP-MS), JEOL JSM-6010LA IntouchScope SEM, Cold Vapor Atomic Fluorescence Spectroscopy (CVAFS), Smiths Detection FTIR Microscope, UV-Vis Spectrometers, ED-XRF Spectro XEPOS, Zeiss LSM 880 Confocal Microscope, Olympus BX53 upright and IX73 inverted fluorescence microscopes, Bruker SENTERRA II micro-FTIR/micro-Raman spectrometer, Nanoflow HPLC system with Thermo-Forma EASY-nLC 1200 System, Orbitrap Fusion Lumos Tribrid Mass Spectrometer (LC-MS), and UltiMate™ NCP3500RS HPLC system.
Major Equipment: Becton Dickinson FACS Aria III in a BSL-2 biosafety cabinet, Illumina HiSeq 2500 for DNA/RNA high throughput sequencing, cBot Cluster Generation System, Illumina MiSeq, Qubit 2.0 for DNA/RNA quantitation, Agilent Bioanalyzer for DNA/RNA integrity assessment, Covaris DNA fragmentation instrument, Beckman Coulter FXP Dual Multichannel Span-8 robot for sequencing library preparations, NanoString nCounter system FDA-approved for clinical diagnostics, LiCor Odyssey digital imaging station, c-Digit chemiluminescence system, EVOS cell imaging system, and visible and fluorescence plate readers.